Proteasome subunit beta type-9 (PSMB9)

About Proteasome subunit beta type-9

Proteasome subunit beta type-9 (PSMB9) is a protein from Homo sapiens identified by UniProt accession P28065, 219 residues long. MolForge cross-references it against 0 known binders and 308 disease associations.

Target properties

Protein name	Proteasome subunit beta type-9
UniProt accession	P28065
Gene	PSMB9
Organism	Homo sapiens
Length	219 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (308)

Diseases linked to this target (Open Targets).

MHC class I deficiency · score 0.56
proteasome-associated autoinflammatory syndrome 3 · score 0.54
HIV infection · score 0.46
proteosome-associated autoinflammatory syndrome · score 0.31
glioblastoma multiforme · score 0.29
urinary bladder cancer · score 0.28
gastric adenocarcinoma · score 0.27
Proteasome disability syndrome · score 0.27
multiple myeloma · score 0.25
genetic disorder · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P28065-F1	alphafold	PREDICTED	90.91	—

Amino-acid sequence (219 residues)

MLRAGAPTGD LPRAGEVHTG TTIMAVEFDG GVVMGSDSRV SAGEAVVNRV FDKLSPLHER IYCALSGSAA DAQAVADMAA YQLELHGIEL EEPPLVLAAA NVVRNISYKY REDLSAHLMV AGWDQREGGQ VYGTLGGMLT RQPFAIGGSG STFIYGYVDA AYKPGMSPEE CRRFTTDAIA LAMSRDGSSG GVIYLVTITA AGVDHRVILG NELPKFYDE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards