About Alcohol dehydrogenase 6
Alcohol dehydrogenase 6 (ADH6) is a protein
from Homo sapiens identified by UniProt accession
P28332, 368 residues long.
MolForge cross-references it against 0 known binders and
64 disease associations.
Target properties
| Protein name | Alcohol dehydrogenase 6 |
|---|
| UniProt accession | P28332 |
|---|
| Gene | ADH6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 368 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (64)
Diseases linked to this target (Open Targets).
- alcohol use disorder measurement · score 0.15
- longitudinal alcohol consumption measurement · score 0.14
- serum metabolite measurement · score 0.12
- cutaneous melanoma · score 0.12
- urinary bladder cancer · score 0.11
- eosinophil count · score 0.08
- hepatocellular carcinoma · score 0.06
- Barrett's esophagus · score 0.06
- cancer · score 0.05
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P28332-F1 | alphafold | PREDICTED | 95.97 | — |
Amino-acid sequence (368 residues)
MSTTGQVIRC KAAILWKPGA PFSIEEVEVA PPKAKEVRIK VVATGLCGTE MKVLGSKHLD LLYPTILGHE GAGIVESIGE GVSTVKPGDK VITLFLPQCG ECTSCLNSEG NFCIQFKQSK TQLMSDGTSR FTCKGKSIYH FGNTSTFCEY TVIKEISVAK IDAVAPLEKV CLISCGFSTG FGAAINTAKV TPGSTCAVFG LGGVGLSVVM GCKAAGAARI IGVDVNKEKF KKAQELGATE CLNPQDLKKP IQEVLFDMTD AGIDFCFEAI GNLDVLAAAL ASCNESYGVC VVVGVLPASV QLKISGQLFF SGRSLKGSVF GGWKSRQHIP KLVADYMAEK LNLDPLITHT LNLDKINEAV ELMKTGKW
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