Homeobox protein Hox-D9 (HOXD9)

About Homeobox protein Hox-D9

Homeobox protein Hox-D9 (HOXD9) is a protein from Homo sapiens identified by UniProt accession P28356, 352 residues long. MolForge cross-references it against 0 known binders and 229 disease associations.

Target properties

Protein name	Homeobox protein Hox-D9
UniProt accession	P28356
Gene	HOXD9
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (229)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.32
hair shape measurement · score 0.15
erythrocyte count · score 0.15
balding measurement · score 0.14
alopecia · score 0.12
androgenetic alopecia · score 0.11
hair colour measurement · score 0.11
urate measurement · score 0.10
heel bone mineral density · score 0.10
gonorrhea · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P28356-F1	alphafold	PREDICTED	57.14	—

Amino-acid sequence (352 residues)

MLGGSAGRLK MSSSGTLSNY YVDSLIGHEG DEVFAARFGP PGPGAQGRPA GVADGPAATA AEFASCSFAP RSAVFSASWS AVPSQPPAAA AMSGLYHPYV PPPPLAASAS EPGRYVRSWM EPLPGFPGGA GGGGGGGGGG PGRGPSPGPS GPANGRHYGI KPETRAAPAP ATAASTTSSS STSLSSSSKR TECSVARESQ GSSGPEFSCN SFLQEKAAAA TGGTGPGAGI GAATGTGGSS EPSACSDHPI PGCSLKEEEK QHSQPQQQQL DPNNPAANWI HARSTRKKRC PYTKYQTLEL EKEFLFNMYL TRDRRYEVAR ILNLTERQVK IWFQNRRMKM KKMSKEKCPK GD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards