Protein S100-A2 (S100A2)

About Protein S100-A2

Protein S100-A2 (S100A2) is a protein from Homo sapiens identified by UniProt accession P29034, 98 residues long. MolForge cross-references it against 0 known binders and 161 disease associations.

Target properties

Protein name	Protein S100-A2
UniProt accession	P29034
Gene	S100A2
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (161)

Diseases linked to this target (Open Targets).

optic cup area measurement · score 0.15
neoplasm · score 0.09
breast cancer · score 0.08
endometrial carcinoma · score 0.07
non-small cell lung carcinoma · score 0.07
urinary bladder carcinoma · score 0.05
oral squamous cell carcinoma · score 0.05
blood protein measurement · score 0.05
laryngeal carcinoma · score 0.05
pachyonychia congenita · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P29034-F1	alphafold	PREDICTED	87.42	—

Amino-acid sequence (98 residues)

MMCSSLEQAL AVLVTTFHKY SCQEGDKFKL SKGEMKELLH KELPSFVGEK VDEEGLKKLM GSLDENSDQQ VDFQEYAVFL ALITVMCNDF FQGCPDRP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards