Protein S100-G (S100G)

About Protein S100-G

Protein S100-G (S100G) is a protein from Homo sapiens identified by UniProt accession P29377, 79 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein name	Protein S100-G
UniProt accession	P29377
Gene	S100G
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (46)

Diseases linked to this target (Open Targets).

Pituitary prolactin cell adenoma · score 0.03
colitis · score 0.01
type 1 diabetes mellitus · score 0.01
Schnyder corneal dystrophy · score 0.01
Disseminated Peritoneal Leiomyomatosis · score 0.01
endometrial carcinoma · score 0.01
type 2 diabetes mellitus · score 0.01
reading · score 0.01
rectal neoplasm · score 0.01
Hypoinsulinemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P29377-F1	alphafold	PREDICTED	86.63	—

Amino-acid sequence (79 residues)

MSTKKSPEEL KRIFEKYAAK EGDPDQLSKD ELKLLIQAEF PSLLKGPNTL DDLFQELDKN GDGEVSFEEF QVLVKKISQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards