Elongation factor 1-delta (EEF1D)

About Elongation factor 1-delta

Elongation factor 1-delta (EEF1D) is a protein from Homo sapiens identified by UniProt accession P29692, 281 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.

Target properties

Protein name	Elongation factor 1-delta
UniProt accession	P29692
Gene	EEF1D
Organism	Homo sapiens
Length	281 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (116)

Diseases linked to this target (Open Targets).

autosomal recessive non-syndromic intellectual disability · score 0.33
Neurodevelopmental disorder · score 0.30
myelodysplastic syndrome associated with isolated del(5q) · score 0.27
protein measurement · score 0.18
serum alanine aminotransferase measurement · score 0.16
genetic disorder · score 0.15
endometrial cancer · score 0.11
Red cell distribution width · score 0.11
osteosarcoma · score 0.07
neoplasm · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P29692-F1	alphafold	PREDICTED	72.97	—

Amino-acid sequence (281 residues)

MATNFLAHEK IWFDKFKYDD AERRFYEQMN GPVAGASRQE NGASVILRDI ARARENIQKS LAGSSGPGAS SGTSGDHGEL VVRIASLEVE NQSLRGVVQE LQQAISKLEA RLNVLEKSSP GHRATAPQTQ HVSPMRQVEP PAKKPATPAE DDEDDDIDLF GSDNEEEDKE AAQLREERLR QYAEKKAKKP ALVAKSSILL DVKPWDDETD MAQLEACVRS IQLDGLVWGA SKLVPVGYGI RKLQIQCVVE DDKVGTDLLE EEITKFEEHV QSVDIAAFNK I

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards