About Cellular retinoic acid-binding protein 1
Cellular retinoic acid-binding protein 1 (CRABP1) is a protein
from Homo sapiens identified by UniProt accession
P29762, 137 residues long.
MolForge cross-references it against 0 known binders and
148 disease associations.
Target properties
| Protein name | Cellular retinoic acid-binding protein 1 |
|---|
| UniProt accession | P29762 |
|---|
| Gene | CRABP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 137 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (148)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- self reported educational attainment · score 0.15
- neoplasm · score 0.07
- cancer · score 0.07
- neuroblastoma · score 0.05
- mean corpuscular hemoglobin · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
- 46,XY complete gonadal dysgenesis · score 0.05
- mean corpuscular volume · score 0.04
- 46,XX testicular disorder of sex development · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P29762-F1 | alphafold | PREDICTED | 95.95 | — |
Amino-acid sequence (137 residues)
MPNFAGTWKM RSSENFDELL KALGVNAMLR KVAVAAASKP HVEIRQDGDQ FYIKTSTTVR TTEINFKVGE GFEEETVDGR KCRSLATWEN ENKIHCTQTL LEGDGPKTYW TRELANDELI LTFGADDVVC TRIYVRE
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