CD40 ligand (CD40LG)

About CD40 ligand

CD40 ligand (CD40LG) is a protein from Homo sapiens identified by UniProt accession P29965, 261 residues long. MolForge cross-references it against 0 known binders and 2,196 disease associations.

Target properties

Protein name	CD40 ligand
UniProt accession	P29965
Gene	CD40LG
Organism	Homo sapiens
Length	261 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P29965-F1	alphafold	PREDICTED	82.64	—

Amino-acid sequence (261 residues)

MIETYNQTSP RSAATGLPIS MKIFMYLLTV FLITQMIGSA LFAVYLHRRL DKIEDERNLH EDFVFMKTIQ RCNTGERSLS LLNCEEIKSQ FEGFVKDIML NKEETKKENS FEMQKGDQNP QIAAHVISEA SSKTTSVLQW AEKGYYTMSN NLVTLENGKQ LTVKRQGLYY IYAQVTFCSN REASSQAPFI ASLCLKSPGR FERILLRAAN THSSAKPCGQ QSIHLGGVFE LQPGASVFVN VTDPSQVSHG TGFTSFGLLK L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards