About Peroxiredoxin-6
Peroxiredoxin-6 (PRDX6) is a protein
from Homo sapiens identified by UniProt accession
P30041, 224 residues long.
MolForge cross-references it against 0 known binders and
178 disease associations.
Target properties
| Protein name | Peroxiredoxin-6 |
|---|
| UniProt accession | P30041 |
|---|
| Gene | PRDX6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (178)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.35
- systemic lupus erythematosus · score 0.34
- blood protein measurement · score 0.30
- systemic scleroderma · score 0.29
- myositis · score 0.24
- breast adenocarcinoma · score 0.18
- adolescent idiopathic scoliosis · score 0.15
- serum IgM measurement · score 0.11
- lung adenocarcinoma · score 0.08
- non-small cell lung carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30041-F1 | alphafold | PREDICTED | 96.62 | — |
Amino-acid sequence (224 residues)
MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE FAKRNVKLIA LSIDSVEDHL AWSKDINAYN CEEPTEKLPF PIIDDRNREL AILLGMLDPA EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP
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