About Peroxiredoxin-5, mitochondrial
Peroxiredoxin-5, mitochondrial (PRDX5) is a protein
from Homo sapiens identified by UniProt accession
P30044, 214 residues long.
MolForge cross-references it against 0 known binders and
310 disease associations.
Target properties
| Protein name | Peroxiredoxin-5, mitochondrial |
|---|
| UniProt accession | P30044 |
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| Gene | PRDX5 |
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| Organism | Homo sapiens |
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| Length | 214 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (310)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- breast adenocarcinoma · score 0.25
- urinary bladder cancer · score 0.12
- body fat percentage · score 0.11
- reticulocyte count · score 0.11
- non-small cell lung carcinoma · score 0.09
- body mass index · score 0.09
- neoplasm · score 0.08
- type 2 diabetes mellitus · score 0.08
- psoriasis · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30044-F1 | alphafold | PREDICTED | 85.32 | — |
Amino-acid sequence (214 residues)
MGLAGVCALR RSAGYILVGG AGGQSAAAAA RRYSEGEWAS GGVRSFSRAA AAMAPIKVGD AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL
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