About ATP synthase F(1) complex subunit delta, mitochondrial
ATP synthase F(1) complex subunit delta, mitochondrial (ATP5F1D) is a protein
from Homo sapiens identified by UniProt accession
P30049, 168 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | ATP synthase F(1) complex subunit delta, mitochondrial |
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| UniProt accession | P30049 |
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| Gene | ATP5F1D |
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| Organism | Homo sapiens |
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| Length | 168 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (54)
Diseases linked to this target (Open Targets).
- Isolated ATP synthase deficiency · score 0.61
- mitochondrial complex 5 (ATP synthase) deficiency nuclear type 5 · score 0.57
- mitochondrial disease · score 0.33
- genetic disorder · score 0.19
- erythrocyte count · score 0.17
- creatinine measurement · score 0.11
- type 2 diabetes mellitus · score 0.10
- hemoglobin measurement · score 0.07
- lymphocyte percentage of leukocytes · score 0.06
- lymphocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30049-F1 | alphafold | PREDICTED | 84.86 | — |
Amino-acid sequence (168 residues)
MLPAALLRRP GLGRLVRHAR AYAEAAAAPA AASGPNQMSF TFASPTQVFF NGANVRQVDV PTLTGAFGIL AAHVPTLQVL RPGLVVVHAE DGTTSKYFVS SGSIAVNADS SVQLLAEEAV TLDMLDLGAA KANLEKAQAE LVGTADEATR AEIQIRIEAN EALVKALE
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