About Large ribosomal subunit protein uL11
Large ribosomal subunit protein uL11 (RPL12) is a protein
from Homo sapiens identified by UniProt accession
P30050, 165 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL11 |
|---|
| UniProt accession | P30050 |
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| Gene | RPL12 |
|---|
| Organism | Homo sapiens |
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| Length | 165 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- neurodegenerative disease · score 0.46
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- thyroid gland adenocarcinoma · score 0.18
- platelet count · score 0.12
- aniridia · score 0.09
- diffuse large B-cell lymphoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30050-F1 | alphafold | PREDICTED | 70.93 | — |
Amino-acid sequence (165 residues)
MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRITV KLTIQNRQAQ IEVVPSASAL IIKALKEPPR DRKKQKNIKH SGNITFDEIV NIARQMRHRS LARELSGTIK EILGTAQSVG CNVDGRHPHD IIDDINSGAV ECPAS
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