UMP-CMP kinase (CMPK1)

Homo sapiens — UniProt P30085

Gene: CMPK1Homo sapiensSwissProt reviewed

About UMP-CMP kinase

UMP-CMP kinase (CMPK1) is a protein from Homo sapiens identified by UniProt accession P30085, 196 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein nameUMP-CMP kinase
UniProt accessionP30085
GeneCMPK1
OrganismHomo sapiens
Length196 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (96)

Diseases linked to this target (Open Targets).

  • Alzheimer disease · score 0.27
  • lysosomal storage disease · score 0.27
  • Parkinson disease · score 0.27
  • multiple sclerosis · score 0.27
  • neurodegenerative disease · score 0.27
  • refractive error measurement · score 0.25
  • corneal topography · score 0.24
  • mean corpuscular hemoglobin · score 0.17
  • neuroinflammatory disorder · score 0.17
  • Red cell distribution width · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P30085-F1alphafoldPREDICTED96.96—

Amino-acid sequence (196 residues)

MKPLVVFVLG GPGAGKGTQC ARIVEKYGYT HLSAGELLRD ERKNPDSQYG ELIEKYIKEG KIVPVEITIS LLKREMDQTM AANAQKNKFL IDGFPRNQDN LQGWNKTMDG KADVSFVLFF DCNNEICIER CLERGKSSGR SDDNRESLEK RIQTYLQSTK PIIDLYEEMG KVKKIDASKS VDEVFDEVVQ IFDKEG

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Quick facts

UniProtP30085
GeneCMPK1
OrganismHomo sapiens
Length196
Binders0
Diseases96
View on UniProt