About UMP-CMP kinase
UMP-CMP kinase (CMPK1) is a protein
from Homo sapiens identified by UniProt accession
P30085, 196 residues long.
MolForge cross-references it against 0 known binders and
96 disease associations.
Target properties
| Protein name | UMP-CMP kinase |
| UniProt accession | P30085 |
| Gene | CMPK1 |
| Organism | Homo sapiens |
| Length | 196 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (96)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.27
- lysosomal storage disease · score 0.27
- Parkinson disease · score 0.27
- multiple sclerosis · score 0.27
- neurodegenerative disease · score 0.27
- refractive error measurement · score 0.25
- corneal topography · score 0.24
- mean corpuscular hemoglobin · score 0.17
- neuroinflammatory disorder · score 0.17
- Red cell distribution width · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P30085-F1 | alphafold | PREDICTED | 96.96 | — |
Amino-acid sequence (196 residues)
MKPLVVFVLG GPGAGKGTQC ARIVEKYGYT HLSAGELLRD ERKNPDSQYG ELIEKYIKEG KIVPVEITIS LLKREMDQTM AANAQKNKFL IDGFPRNQDN LQGWNKTMDG KADVSFVLFF DCNNEICIER CLERGKSSGR SDDNRESLEK RIQTYLQSTK PIIDLYEEMG KVKKIDASKS VDEVFDEVVQ IFDKEG
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