Phosphatidylethanolamine-binding protein 1 (PEBP1)

About Phosphatidylethanolamine-binding protein 1

Phosphatidylethanolamine-binding protein 1 (PEBP1) is a protein from Homo sapiens identified by UniProt accession P30086, 187 residues long. MolForge cross-references it against 0 known binders and 288 disease associations.

Target properties

Protein name	Phosphatidylethanolamine-binding protein 1
UniProt accession	P30086
Gene	PEBP1
Organism	Homo sapiens
Length	187 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (288)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.29
breast adenocarcinoma · score 0.29
cutaneous melanoma · score 0.19
Red cell distribution width · score 0.18
monocyte count · score 0.13
blood protein measurement · score 0.12
neoplasm · score 0.12
cancer · score 0.11
non-small cell lung carcinoma · score 0.10
nonpapillary renal cell carcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P30086-F1	alphafold	PREDICTED	97.32	—

Amino-acid sequence (187 residues)

MPVDLSKWSG PLSLQEVDEQ PQHPLHVTYA GAAVDELGKV LTPTQVKNRP TSISWDGLDS GKLYTLVLTD PDAPSRKDPK YREWHHFLVV NMKGNDISSG TVLSDYVGSG PPKGTGLHRY VWLVYEQDRP LKCDEPILSN RSGDHRGKFK VASFRKKYEL RAPVAGTCYQ AEWDDYVPKL YEQLSGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards