High affinity immunoglobulin epsilon receptor…

About High affinity immunoglobulin epsilon receptor subunit gamma

High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) is a protein from Homo sapiens identified by UniProt accession P30273, 86 residues long. MolForge cross-references it against 0 known binders and 443 disease associations.

Target properties

Protein name	High affinity immunoglobulin epsilon receptor subunit gamma
UniProt accession	P30273
Gene	FCER1G
Organism	Homo sapiens
Length	86 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (443)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.36
platelet component distribution width · score 0.32
platelet count · score 0.31
blood protein measurement · score 0.30
allergic rhinitis · score 0.28
mean corpuscular hemoglobin · score 0.25
asthma · score 0.24
allergic disease · score 0.24
Eczematoid dermatitis · score 0.22
mean corpuscular volume · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P30273-F1	alphafold	PREDICTED	72.17	—

Amino-acid sequence (86 residues)

MIPAVVLLLL LLVEQAAALG EPQLCYILDA ILFLYGIVLT LLYCRLKIQV RKAAITSYEK SDGVYTGLST RNQETYETLK HEKPPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G)