G1/S-specific cyclin-D3 (CCND3)

About G1/S-specific cyclin-D3

G1/S-specific cyclin-D3 (CCND3) is a protein from Homo sapiens identified by UniProt accession P30281, 292 residues long. MolForge cross-references it against 0 known binders and 408 disease associations.

Target properties

Protein name	G1/S-specific cyclin-D3
UniProt accession	P30281
Gene	CCND3
Organism	Homo sapiens
Length	292 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P30281-F1	alphafold	PREDICTED	86.97	—

Amino-acid sequence (292 residues)

MELLCCEGTR HAPRAGPDPR LLGDQRVLQS LLRLEERYVP RASYFQCVQR EIKPHMRKML AYWMLEVCEE QRCEEEVFPL AMNYLDRYLS CVPTRKAQLQ LLGAVCMLLA SKLRETTPLT IEKLCIYTDH AVSPRQLRDW EVLVLGKLKW DLAAVIAHDF LAFILHRLSL PRDRQALVKK HAQTFLALCA TDYTFAMYPP SMIATGSIGA AVQGLGACSM SGDELTELLA GITGTEVDCL RACQEQIEAA LRESLREASQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI HL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards