About Heme oxygenase 2
Heme oxygenase 2 (HMOX2) is a protein
from Homo sapiens identified by UniProt accession
P30519, 316 residues long.
MolForge cross-references it against 0 known binders and
209 disease associations.
Target properties
| Protein name | Heme oxygenase 2 |
|---|
| UniProt accession | P30519 |
|---|
| Gene | HMOX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 316 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (209)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.23
- osteoarthritis, knee · score 0.14
- platelet count · score 0.11
- vitamin D measurement · score 0.10
- reticulocyte count · score 0.09
- hair colour measurement · score 0.09
- eosinophil count · score 0.09
- cancer · score 0.08
- Immature Reticulocyte Fraction Measurement · score 0.07
- IGF-1 measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30519-F1 | alphafold | PREDICTED | 80.31 | — |
Amino-acid sequence (316 residues)
MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRKCPFYAA EQDKGALEGS SCPFRTAMAV LRKPSLQFIL AAGVALAAGL LAWYYM
Explore Heme oxygenase 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets