Olfactory receptor 1E1 (OR1E1)

About Olfactory receptor 1E1

Olfactory receptor 1E1 (OR1E1) is a protein from Homo sapiens identified by UniProt accession P30953, 314 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Olfactory receptor 1E1
UniProt accession	P30953
Gene	OR1E1
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

neuroblastoma · score 0.21
hepatocellular carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
Lynch syndrome · score 0.08
colorectal cancer, susceptibility to, 3 · score 0.06
inflammatory bowel disease · score 0.06
Testicular regression syndrome · score 0.06
Hirschsprung disease · score 0.06
Meckel's diverticulum · score 0.06
familial adenomatous polyposis 2 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P30953-F1	alphafold	PREDICTED	88.48	—

Amino-acid sequence (314 residues)

MMGQNQTSIS DFLLLGLPIQ PEQQNLCYAL FLAMYLTTLL GNLLIIVLIR LDSHLHTPMY LFLSNLSFSD LCFSSVTIPK LLQNMQNQDP SIPYADCLTQ MYFFLLFGDL ESFLLVAMAY DRYVAICFPL HYTAIMSPML CLALVALSWV LTTFHAMLHT LLMARLCFCA DNVIPHFFCD MSALLKLAFS DTRVNEWVIF IMGGLILVIP FLLILGSYAR IVSSILKVPS SKGICKAFST CGSHLSVVSL FYGTVIGLYL CSSANSSTLK DTVMAMMYTV VTPMLNPFIY SLRNRDMKGA LSRVIHQKKT FFSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards