About Neurotensin/neuromedin N
Neurotensin/neuromedin N (NTS) is a protein
from Homo sapiens identified by UniProt accession
P30990, 170 residues long.
MolForge cross-references it against 0 known binders and
298 disease associations.
Target properties
| Protein name | Neurotensin/neuromedin N |
|---|
| UniProt accession | P30990 |
|---|
| Gene | NTS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 170 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (298)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.26
- neurodegenerative disease · score 0.26
- Alzheimer disease · score 0.26
- multiple sclerosis · score 0.26
- lysosomal storage disease · score 0.26
- breast ductal adenocarcinoma · score 0.11
- mathematical ability · score 0.11
- hair colour measurement · score 0.09
- diffuse plaque measurement · score 0.08
- Crohn's disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P30990-F1 | alphafold | PREDICTED | 61.35 | — |
Amino-acid sequence (170 residues)
MMAGMKIQLV CMLLLAFSSW SLCSDSEEEM KALEADFLTN MHTSKISKAH VPSWKMTLLN VCSLVNNLNS PAEETGEVHE EELVARRKLP TALDGFSLEA MLTIYQLHKI CHSRAFQHWE LIQEDILDTG NDKNGKEEVI KRKIPYILKR QLYENKPRRP YILKRDSYYY
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