Lipocalin-1 (LCN1)

About Lipocalin-1

Lipocalin-1 (LCN1) is a protein from Homo sapiens identified by UniProt accession P31025, 176 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	Lipocalin-1
UniProt accession	P31025
Gene	LCN1
Organism	Homo sapiens
Length	176 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.25
cutaneous melanoma · score 0.15
chronic obstructive pulmonary disease · score 0.05
parental longevity · score 0.04
neoplasm · score 0.03
bone density · score 0.03
urate measurement · score 0.03
infect · score 0.02
infection · score 0.02
gut microbiome measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P31025-F1	alphafold	PREDICTED	88.58	—

Amino-acid sequence (176 residues)

MKPLLLAVSL GLIAALQAHH LLASDEEIQD VSGTWYLKAM TVDREFPEMN LESVTPMTLT TLEGGNLEAK VTMLISGRCQ EVKAVLEKTD EPGKYTADGG KHVAYIIRSH VKDHYIFYCE GELHGKPVRG VKLVGRDPKN NLEALEDFEK AAGARGLSTE SILIPRQSET CSPGSD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards