Protein S100-A7 (S100A7)

About Protein S100-A7

Protein S100-A7 (S100A7) is a protein from Homo sapiens identified by UniProt accession P31151, 101 residues long. MolForge cross-references it against 0 known binders and 267 disease associations.

Target properties

Protein name	Protein S100-A7
UniProt accession	P31151
Gene	S100A7
Organism	Homo sapiens
Length	101 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (267)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.23
cutaneous melanoma · score 0.22
head and neck squamous cell carcinoma · score 0.20
esophageal squamous cell carcinoma · score 0.20
urinary bladder carcinoma · score 0.20
squamous cell lung carcinoma · score 0.20
pancreatic ductal adenocarcinoma · score 0.19
thyroid carcinoma · score 0.19
prostate adenocarcinoma · score 0.19
gastric adenocarcinoma · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P31151-F1	alphafold	PREDICTED	95.34	—

Amino-acid sequence (101 residues)

MSNTQAERSI IGMIDMFHKY TRRDDKIEKP SLLTMMKENF PNFLSACDKK GTNYLADVFE KKDKNEDKKI DFSEFLSLLG DIATDYHKQS HGAAPCSGGS Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards