About Homeobox protein Hox-A10
Homeobox protein Hox-A10 (HOXA10) is a protein
from Homo sapiens identified by UniProt accession
P31260, 410 residues long.
MolForge cross-references it against 0 known binders and
385 disease associations.
Target properties
| Protein name | Homeobox protein Hox-A10 |
|---|
| UniProt accession | P31260 |
|---|
| Gene | HOXA10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 410 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (385)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.37
- vital capacity · score 0.26
- neurodegenerative disease · score 0.26
- mean corpuscular hemoglobin · score 0.21
- hematocrit · score 0.20
- genetic disorder · score 0.19
- hypertension · score 0.17
- bone density · score 0.17
- mean corpuscular hemoglobin concentration · score 0.14
- body fat percentage · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31260-F1 | alphafold | PREDICTED | 59.12 | — |
Amino-acid sequence (410 residues)
MSARKGYLLP SPNYPTTMSC SESPAANSFL VDSLISSGRG EAGGGGGGAG GGGGGGYYAH GGVYLPPAAD LPYGLQSCGL FPTLGGKRNE AASPGSGGGG GGLGPGAHGY GPSPIDLWLD APRSCRMEPP DGPPPPPQQQ PPPPPQPPQP APQATSCSFA QNIKEESSYC LYDSADKCPK VSATAAELAP FPRGPPPDGC ALGTSSGVPV PGYFRLSQAY GTAKGYGSGG GGAQQLGAGP FPAQPPGRGF DLPPALASGS ADAARKERAL DSPPPPTLAC GSGGGSQGDE EAHASSSAAE ELSPAPSESS KASPEKDSLG NSKGENAANW LTAKSGRKKR CPYTKHQTLE LEKEFLFNMY LTRERRLEIS RSVHLTDRQV KIWFQNRRMK LKKMNRENRI RELTANFNFS
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