About Homeobox protein Hox-A6
Homeobox protein Hox-A6 (HOXA6) is a protein
from Homo sapiens identified by UniProt accession
P31267, 233 residues long.
MolForge cross-references it against 0 known binders and
78 disease associations.
Target properties
| Protein name | Homeobox protein Hox-A6 |
|---|
| UniProt accession | P31267 |
|---|
| Gene | HOXA6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 233 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (78)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- neutrophil count · score 0.18
- monocyte count · score 0.15
- platelet count · score 0.12
- leukocyte count · score 0.12
- lymphocyte count · score 0.11
- monocyte percentage of leukocytes · score 0.11
- BMI-adjusted waist circumference · score 0.10
- bone quantitative ultrasound measurement · score 0.09
- bone density · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31267-F1 | alphafold | PREDICTED | 62.86 | — |
Amino-acid sequence (233 residues)
MSSYFVNPTF PGSLPSGQDS FLGQLPLYQA GYDALRPFPA SYGASSLPDK TYTSPCFYQQ SNSVLACNRA SYEYGASCFY SDKDLSGASP SGSGKQRGPG DYLHFSPEQQ YKPDSSSGQG KALHDEGADR KYTSPVYPWM QRMNSCAGAV YGSHGRRGRQ TYTRYQTLEL EKEFHFNRYL TRRRRIEIAN ALCLTERQIK IWFQNRRMKW KKENKLINST QPSGEDSEAK AGE
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