About Homeobox protein Hox-A7
Homeobox protein Hox-A7 (HOXA7) is a protein
from Homo sapiens identified by UniProt accession
P31268, 230 residues long.
MolForge cross-references it against 0 known binders and
114 disease associations.
Target properties
| Protein name | Homeobox protein Hox-A7 |
|---|
| UniProt accession | P31268 |
|---|
| Gene | HOXA7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 230 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (114)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.32
- neutrophil count · score 0.27
- BMI-adjusted waist circumference · score 0.21
- FEV/FVC ratio · score 0.19
- monocyte count · score 0.16
- platelet count · score 0.14
- mosaic loss of chromosome Y measurement · score 0.12
- leukocyte count · score 0.12
- heel bone mineral density · score 0.11
- myeloid white cell count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31268-F1 | alphafold | PREDICTED | 63.13 | — |
Amino-acid sequence (230 residues)
MSSSYYVNAL FSKYTAGASL FQNAEPTSCS FAPNSQRSGY GAGAGAFAST VPGLYNVNSP LYQSPFASGY GLGADAYGNL PCASYDQNIP GLCSDLAKGA CDKTDEGALH GAAEANFRIY PWMRSSGPDR KRGRQTYTRY QTLELEKEFH FNRYLTRRRR IEIAHALCLT ERQIKIWFQN RRMKWKKEHK DEGPTAAAAP EGAVPSAAAT AAADKADEED DDEEEEDEEE
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