Homeobox protein Hox-A9 (HOXA9)

About Homeobox protein Hox-A9

Homeobox protein Hox-A9 (HOXA9) is a protein from Homo sapiens identified by UniProt accession P31269, 272 residues long. MolForge cross-references it against 0 known binders and 295 disease associations.

Target properties

Protein name	Homeobox protein Hox-A9
UniProt accession	P31269
Gene	HOXA9
Organism	Homo sapiens
Length	272 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (295)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.39
erythrocyte count · score 0.39
lung adenocarcinoma · score 0.37
lung carcinoma · score 0.37
Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation · score 0.37
Endometrial Endometrioid Adenocarcinoma · score 0.37
mean corpuscular hemoglobin concentration · score 0.35
monocyte count · score 0.34
mean corpuscular hemoglobin · score 0.33
heel bone mineral density · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P31269-F1	alphafold	PREDICTED	61.61	—

Amino-acid sequence (272 residues)

MATTGALGNY YVDSFLLGAD AADELSVGRY APGTLGQPPR QAATLAEHPD FSPCSFQSKA TVFGASWNPV HAAGANAVPA AVYHHHHHHP YVHPQAPVAA AAPDGRYMRS WLEPTPGALS FAGLPSSRPY GIKPEPLSAR RGDCPTLDTH TLSLTDYACG SPPVDREKQP SEGAFSENNA ENESGGDKPP IDPNNPAANW LHARSTRKKR CPYTKHQTLE LEKEFLFNMY LTRDRRYEVA RLLNLTERQV KIWFQNRRMK MKKINKDRAK DE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards