About Homeobox protein Hox-C9
Homeobox protein Hox-C9 (HOXC9) is a protein
from Homo sapiens identified by UniProt accession
P31274, 260 residues long.
MolForge cross-references it against 0 known binders and
193 disease associations.
Target properties
| Protein name | Homeobox protein Hox-C9 |
|---|
| UniProt accession | P31274 |
|---|
| Gene | HOXC9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 260 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (193)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.37
- BMI-adjusted waist-hip ratio · score 0.35
- vital capacity · score 0.22
- BMI-adjusted waist circumference · score 0.16
- waist-hip ratio · score 0.14
- platelet crit · score 0.12
- spine bone size · score 0.12
- neuroblastoma · score 0.09
- leukocyte count · score 0.09
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31274-F1 | alphafold | PREDICTED | 64.17 | — |
Amino-acid sequence (260 residues)
MSATGPISNY YVDSLISHDN EDLLASRFPA TGAHPAAARP SGLVPDCSDF PSCSFAPKPA VFSTSWAPVP SQSSVVYHPY GPQPHLGADT RYMRTWLEPL SGAVSFPSFP AGGRHYALKP DAYPGRRADC GPGEGRSYPD YMYGSPGELR DRAPQTLPSP EADALAGSKH KEEKADLDPS NPVANWIHAR STRKKRCPYT KYQTLELEKE FLFNMYLTRD RRYEVARVLN LTERQVKIWF QNRRMKMKKM NKEKTDKEQS
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