About Syndecan-4
Syndecan-4 (SDC4) is a protein
from Homo sapiens identified by UniProt accession
P31431, 198 residues long.
MolForge cross-references it against 0 known binders and
380 disease associations.
Target properties
| Protein name | Syndecan-4 |
|---|
| UniProt accession | P31431 |
|---|
| Gene | SDC4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (380)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.54
- non-small cell lung carcinoma · score 0.44
- lung adenocarcinoma · score 0.37
- acinar lung adenocarcinoma · score 0.37
- gastric adenocarcinoma · score 0.31
- cutaneous melanoma · score 0.29
- neurodegenerative disease · score 0.28
- Signet Ring Cell Gastric Adenocarcinoma · score 0.28
- diffuse gastric adenocarcinoma · score 0.28
- squamous cell lung carcinoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P31431-F1 | alphafold | PREDICTED | 63.27 | — |
Amino-acid sequence (198 residues)
MAPARLFALL LFFVGGVAES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE ESEDVSNKVS MSSTVQGSNI FERTEVLAAL IVGGIVGILF AVFLILLLMY RMKKKDEGSY DLGKKPIYKK APTNEFYA
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