Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3)

About Heterogeneous nuclear ribonucleoprotein H3

Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) is a protein from Homo sapiens identified by UniProt accession P31942, 346 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Heterogeneous nuclear ribonucleoprotein H3
UniProt accession	P31942
Gene	HNRNPH3
Organism	Homo sapiens
Length	346 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

protein measurement · score 0.11
body height · score 0.07
optic disc size measurement · score 0.06
Pituitary Gland Adenoma · score 0.02
body weight · score 0.02
neoplasm · score 0.01
benign meningioma · score 0.01
salivary duct carcinoma · score 0.01
infection · score 0.01
ulcerative colitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P31942-F1	alphafold	PREDICTED	60.85	—

Amino-acid sequence (346 residues)

MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY DPPRRLLGQR PGPYDRPIGG RGGYYGAGRG SMYDRMRRGG DGYDGGYGGF DDYGGYNNYG YGNDGFDDRM RDGRGMGGHG YGGAGDASSG FHGGHFVHMR GLPFRATEND IANFFSPLNP IRVHIDIGAD GRATGEADVE FVTHEDAVAA MSKDKNNMQH RYIELFLNST PGGGSGMGGS GMGGYGRDGM DNQGGYGSVG RMGMGNNYSG GYGTPDGLGG YGRGGGGSGG YYGQGGMSGG GWRGMY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards