About Peroxiredoxin-2
Peroxiredoxin-2 (PRDX2) is a protein
from Homo sapiens identified by UniProt accession
P32119, 198 residues long.
MolForge cross-references it against 0 known binders and
504 disease associations.
Target properties
| Protein name | Peroxiredoxin-2 |
|---|
| UniProt accession | P32119 |
|---|
| Gene | PRDX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (504)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- Alzheimer disease · score 0.45
- Parkinson disease · score 0.33
- multiple sclerosis · score 0.33
- lysosomal storage disease · score 0.32
- mean corpuscular volume · score 0.22
- lung adenocarcinoma · score 0.19
- endometrial cancer · score 0.18
- urinary bladder cancer · score 0.12
- hepatocellular carcinoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P32119-F1 | alphafold | PREDICTED | 97.73 | — |
Amino-acid sequence (198 residues)
MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
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