C-C chemokine receptor type 7 (CCR7)

About C-C chemokine receptor type 7

C-C chemokine receptor type 7 (CCR7) is a protein from Homo sapiens identified by UniProt accession P32248, 378 residues long. MolForge cross-references it against 0 known binders and 789 disease associations.

Target properties

Protein name	C-C chemokine receptor type 7
UniProt accession	P32248
Gene	CCR7
Organism	Homo sapiens
Length	378 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P32248-F1	alphafold	PREDICTED	78.40	—

Amino-acid sequence (378 residues)

MDLGKPMKSV LVVALLVIFQ VCLCQDEVTD DYIGDNTTVD YTLFESLCSK KDVRNFKAWF LPIMYSIICF VGLLGNGLVV LTYIYFKRLK TMTDTYLLNL AVADILFLLT LPFWAYSAAK SWVFGVHFCK LIFAIYKMSF FSGMLLLLCI SIDRYVAIVQ AVSAHRHRAR VLLISKLSCV GIWILATVLS IPELLYSDLQ RSSSEQAMRC SLITEHVEAF ITIQVAQMVI GFLVPLLAMS FCYLVIIRTL LQARNFERNK AIKVIIAVVV VFIVFQLPYN GVVLAQTVAN FNITSSTCEL SKQLNIAYDV TYSLACVRCC VNPFLYAFIG VKFRNDLFKL FKDLGCLSQE QLRQWSSCRH IRRSSMSVEA ETTTTFSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards