About Deoxycytidylate deaminase
Deoxycytidylate deaminase (DCTD) is a protein
from Homo sapiens identified by UniProt accession
P32321, 178 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | Deoxycytidylate deaminase |
|---|
| UniProt accession | P32321 |
|---|
| Gene | DCTD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (122)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.28
- neurodegenerative disease · score 0.27
- self reported educational attainment · score 0.23
- protein measurement · score 0.21
- psoriasis · score 0.18
- Crohn's disease · score 0.18
- juvenile idiopathic arthritis · score 0.18
- ulcerative colitis · score 0.18
- celiac disease · score 0.18
- ankylosing spondylitis · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P32321-F1 | alphafold | PREDICTED | 94.54 | — |
Amino-acid sequence (178 residues)
MSEVSCKKRD DYLEWPEYFM AVAFLSAQRS KDPNSQVGAC IVNSENKIVG IGYNGMPNGC SDDVLPWRRT AENKLDTKYP YVCHAELNAI MNKNSTDVKG CSMYVALFPC NECAKLIIQA GIKEVIFMSD KYHDSDEATA ARLLFNMAGV TFRKFIPKCS KIVIDFDSIN SRPSQKLQ
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