About ETS-related transcription factor Elf-1
ETS-related transcription factor Elf-1 (ELF1) is a protein
from Homo sapiens identified by UniProt accession
P32519, 619 residues long.
MolForge cross-references it against 0 known binders and
78 disease associations.
Target properties
| Protein name | ETS-related transcription factor Elf-1 |
|---|
| UniProt accession | P32519 |
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| Gene | ELF1 |
|---|
| Organism | Homo sapiens |
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| Length | 619 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (78)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.46
- platelet count · score 0.45
- mean corpuscular volume · score 0.44
- lymphocyte percentage of leukocytes · score 0.42
- mean corpuscular hemoglobin concentration · score 0.40
- neutrophil percentage of leukocytes · score 0.40
- systemic lupus erythematosus · score 0.39
- body height · score 0.38
- mean reticulocyte volume · score 0.37
- eosinophil count · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P32519-F1 | alphafold | PREDICTED | 52.79 | — |
Amino-acid sequence (619 residues)
MAAVVQQNDL VFEFASNVME DERQLGDPAI FPAVIVEHVP GADILNSYAG LACVEEPNDM ITESSLDVAE EEIIDDDDDD ITLTVEASCH DGDETIETIE AAEALLNMDS PGPMLDEKRI NNNIFSSPED DMVVAPVTHV SVTLDGIPEV METQQVQEKY ADSPGASSPE QPKRKKGRKT KPPRPDSPAT TPNISVKKKN KDGKGNTIYL WEFLLALLQD KATCPKYIKW TQREKGIFKL VDSKAVSRLW GKHKNKPDMN YETMGRALRY YYQRGILAKV EGQRLVYQFK EMPKDLIYIN DEDPSSSIES SDPSLSSSAT SNRNQTSRSR VSSSPGVKGG ATTVLKPGNS KAAKPKDPVE VAQPSEVLRT VQPTQSPYPT QLFRTVHVVQ PVQAVPEGEA ARTSTMQDET LNSSVQSIRT IQAPTQVPVV VSPRNQQLHT VTLQTVPLTT VIASTDPSAG TGSQKFILQA IPSSQPMTVL KENVMLQSQK AGSPPSIVLG PAQVQQVLTS NVQTICNGTV SVASSPSFSA TAPVVTFSPR SSQLVAHPPG TVITSVIKTQ ETKTLTQEVE KKESEDHLKE NTEKTEQQPQ PYVMVVSSSN GFTSQVAMKQ NELLEPNSF
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