Protein S100-A3 (S100A3)

About Protein S100-A3

Protein S100-A3 (S100A3) is a protein from Homo sapiens identified by UniProt accession P33764, 101 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Protein S100-A3
UniProt accession	P33764
Gene	S100A3
Organism	Homo sapiens
Length	101 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

pulse pressure measurement · score 0.19
blood protein measurement · score 0.19
prostate carcinoma · score 0.11
prostate cancer · score 0.11
Familial prostate cancer · score 0.11
hepatocellular carcinoma · score 0.07
Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
neutropenia, severe congenital, 9, autosomal dominant · score 0.04
monocyte count · score 0.03
neoplasm · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P33764-F1	alphafold	PREDICTED	81.54	—

Amino-acid sequence (101 residues)

MARPLEQAVA AIVCTFQEYA GRCGDKYKLC QAELKELLQK ELATWTPTEF RECDYNKFMS VLDTNKDCEV DFVEYVRSLA CLCLYCHEYF KDCPSEPPCS Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards