About Neurotrophin-4
Neurotrophin-4 (NTF4) is a protein
from Homo sapiens identified by UniProt accession
P34130, 210 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Neurotrophin-4 |
|---|
| UniProt accession | P34130 |
|---|
| Gene | NTF4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- open-angle glaucoma · score 0.64
- cancer · score 0.38
- genetic disorder · score 0.33
- non-small cell lung carcinoma · score 0.06
- Pruritus · score 0.05
- neoplasm · score 0.05
- Romano-Ward syndrome · score 0.05
- dystonia 23 · score 0.04
- proliferative diabetic retinopathy · score 0.04
- Combined hyperlipidemia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P34130-F1 | alphafold | PREDICTED | 78.31 | — |
Amino-acid sequence (210 residues)
MLPLPSCSLP ILLLFLLPSV PIESQPPPST LPPFLAPEWD LLSPRVVLSR GAPAGPPLLF LLEAGAFRES AGAPANRSRR GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Explore Neurotrophin-4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets