About Syndecan-2
Syndecan-2 (SDC2) is a protein
from Homo sapiens identified by UniProt accession
P34741, 201 residues long.
MolForge cross-references it against 0 known binders and
237 disease associations.
Target properties
| Protein name | Syndecan-2 |
|---|
| UniProt accession | P34741 |
|---|
| Gene | SDC2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (237)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.54
- neurodegenerative disease · score 0.50
- FEV/FVC ratio · score 0.39
- appendicular lean mass · score 0.33
- ovarian cancer · score 0.28
- breast adenocarcinoma · score 0.26
- peak expiratory flow · score 0.26
- cutaneous melanoma · score 0.24
- glioblastoma multiforme · score 0.22
- Abnormality of refraction · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P34741-F1 | alphafold | PREDICTED | 60.86 | — |
Amino-acid sequence (201 residues)
MRRAWILLTL GLVACVSAES RAELTSDKDM YLDNSSIEEA SGVYPIDDDD YASASGSGAD EDVESPELTT SRPLPKILLT SAAPKVETTT LNIQNKIPAQ TKSPEETDKE KVHLSDSERK MDPAEEDTNV YTEKHSDSLF KRTEVLAAVI AGGVIGFLFA IFLILLLVYR MRKKDEGSYD LGERKPSSAA YQKAPTKEFY A
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