Macrosialin (CD68)

About Macrosialin

Macrosialin (CD68) is a protein from Homo sapiens identified by UniProt accession P34810, 354 residues long. MolForge cross-references it against 0 known binders and 1,257 disease associations.

Target properties

Protein name	Macrosialin
UniProt accession	P34810
Gene	CD68
Organism	Homo sapiens
Length	354 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P34810-F1	alphafold	PREDICTED	73.21	—

Amino-acid sequence (354 residues)

MRLAVLFSGA LLGLLAAQGT GNDCPHKKSA TLLPSFTVTP TVTESTGTTS HRTTKSHKTT THRTTTTGTT SHGPTTATHN PTTTSHGNVT VHPTSNSTAT SQGPSTATHS PATTSHGNAT VHPTSNSTAT SPGFTSSAHP EPPPPSPSPS PTSKETIGDY TWTNGSQPCV HLQAQIQIRV MYTTQGGGEA WGISVLNPNK TKVQGSCEGA HPHLLLSFPY GHLSFGFMQD LQQKVVYLSY MAVEYNVSFP HAAQWTFSAQ NASLRDLQAP LGQSFSCSNS SIILSPAVHL DLLSLRLQAA QLPHTGVFGQ SFSCPSDRSI LLPLIIGLIL LGLLALVLIA FCIIRRRPSA YQAL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards