Protein EVI2B (EVI2B)

About Protein EVI2B

Protein EVI2B (EVI2B) is a protein from Homo sapiens identified by UniProt accession P34910, 448 residues long. MolForge cross-references it against 0 known binders and 104 disease associations.

Target properties

Protein name	Protein EVI2B
UniProt accession	P34910
Gene	EVI2B
Organism	Homo sapiens
Length	448 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (104)

Diseases linked to this target (Open Targets).

neurofibromatosis type 1 · score 0.42
neurodegenerative disease · score 0.28
sex hormone-binding globulin measurement · score 0.21
blood phosphate measurement · score 0.16
hemorrhoid · score 0.15
cystatin C measurement · score 0.15
platelet count · score 0.15
type 2 diabetes mellitus · score 0.14
alcohol consumption measurement · score 0.14
alkaline phosphatase measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P34910-F1	alphafold	PREDICTED	50.93	—

Amino-acid sequence (448 residues)

MDPKYFILIL FCGHLNNTFF SKTETITTEK QSQPTLFTSS MSQVLANSQN TTGNPLGQPT QFSDTFSGQS ISPAKVTAGQ PTPAVYTSSE KPEAHTSAGQ PLAYNTKQPT PIANTSSQQA VFTSARQLPS ARTSTTQPPK SFVYTFTQQS SSVQIPSRKQ ITVHNPSTQP TSTVKNSPRS TPGFILDTTS NKQTPQKNNY NSIAAILIGV LLTSMLVAII IIVLWKCLRK PVLNDQNWAG RSPFADGETP DICMDNIREN EISTKRTSII SLTPWKPSKS TLLADDLEIK LFESSENIED SNNPKTEKIK DQVNGTSEDS ADGSTVGTAV SSSDDADLPP PPPLLDLEGQ ESNQSDKPTM TIVSPLPNDS TSLPPSLDCL NQDCGDHKSE IIQSFPPLDS LNLPLPPVDF MKNQEDSNLE IQCQEFSIPP NSDQDLNESL PPPPAELL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards