About Trypsin-3
Trypsin-3 (PRSS3) is a protein
from Homo sapiens identified by UniProt accession
P35030, 304 residues long.
MolForge cross-references it against 0 known binders and
225 disease associations.
Target properties
| Protein name | Trypsin-3 |
|---|
| UniProt accession | P35030 |
|---|
| Gene | PRSS3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 304 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (225)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- body height · score 0.24
- lung adenocarcinoma · score 0.24
- cutaneous melanoma · score 0.22
- ovarian cancer · score 0.19
- grip strength measurement · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- emotional symptom measurement · score 0.17
- platelet count · score 0.17
- squamous cell lung carcinoma · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P35030-F1 | alphafold | PREDICTED | 81.77 | — |
Amino-acid sequence (304 residues)
MCGPDDRCPA RWPGPGRAVK CGKGLAAARP GRVERGGAQR GGAGLELHPL LGGRTWRAAR DADGCEALGT VAVPFDDDDK IVGGYTCEEN SLPYQVSLNS GSHFCGGSLI SEQWVVSAAH CYKTRIQVRL GEHNIKVLEG NEQFINAAKI IRHPKYNRDT LDNDIMLIKL SSPAVINARV STISLPTTPP AAGTECLISG WGNTLSFGAD YPDELKCLDA PVLTQAECKA SYPGKITNSM FCVGFLEGGK DSCQRDSGGP VVCNGQLQGV VSWGHGCAWK NRPGVYTKVY NYVDWIKDTI AANS
Explore Trypsin-3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets