About Probetacellulin
Probetacellulin (BTC) is a protein
from Homo sapiens identified by UniProt accession
P35070, 178 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Probetacellulin |
|---|
| UniProt accession | P35070 |
|---|
| Gene | BTC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- cancer · score 0.58
- chronic obstructive pulmonary disease · score 0.49
- FEV/FVC ratio · score 0.46
- smoking status measurement · score 0.33
- forced expiratory volume · score 0.32
- hemorrhoid · score 0.31
- lung adenocarcinoma · score 0.30
- breast adenocarcinoma · score 0.30
- head and neck squamous cell carcinoma · score 0.28
- cutaneous melanoma · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P35070-F1 | alphafold | PREDICTED | 71.95 | — |
Amino-acid sequence (178 residues)
MDRAARCSGA SSLPLLLALA LGLVILHCVV ADGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF YLRGDRGQIL VICLIAVMVV FIILVIGVCT CCHPLRKRRK RKKKEEEMET LGKDITPINE DIEETNIA
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