Interleukin-13 (IL13)

About Interleukin-13

Interleukin-13 (IL13) is a protein from Homo sapiens identified by UniProt accession P35225, 146 residues long. MolForge cross-references it against 0 known binders and 1,155 disease associations.

Target properties

Protein name	Interleukin-13
UniProt accession	P35225
Gene	IL13
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (1155)

Diseases linked to this target (Open Targets).

atopic eczema · score 0.66
asthma · score 0.54
Eczematoid dermatitis · score 0.51
allergic rhinitis · score 0.49
psoriasis · score 0.43
allergic asthma · score 0.37
eosinophilic esophagitis · score 0.37
childhood onset asthma · score 0.37
type 2 diabetes mellitus · score 0.36
serum IgE measurement · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P35225-F1	alphafold	PREDICTED	85.60	—

Amino-acid sequence (146 residues)

MHPLLNPLLL ALGLMALLLT TVIALTCLGG FASPGPVPPS TALRELIEEL VNITQNQKAP LCNGSMVWSI NLTAGMYCAA LESLINVSGC SAIEKTQRML SGFCPHKVSA GQFSSLHVRD TKIEVAQFVK DLLLHLKKLF REGQFN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards