Replication factor C subunit 2 (RFC2)

About Replication factor C subunit 2

Replication factor C subunit 2 (RFC2) is a protein from Homo sapiens identified by UniProt accession P35250, 354 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Replication factor C subunit 2
UniProt accession	P35250
Gene	RFC2
Organism	Homo sapiens
Length	354 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P35250-F1	alphafold	PREDICTED	86.68	—

Amino-acid sequence (354 residues)

MEVEAVCGGA GEVEAQDSDP APAFSKAPGS AGHYELPWVE KYRPVKLNEI VGNEDTVSRL EVFAREGNVP NIIIAGPPGT GKTTSILCLA RALLGPALKD AMLELNASND RGIDVVRNKI KMFAQQKVTL PKGRHKIIIL DEADSMTDGA QQALRRTMEI YSKTTRFALA CNASDKIIEP IQSRCAVLRY TKLTDAQILT RLMNVIEKER VPYTDDGLEA IIFTAQGDMR QALNNLQSTF SGFGFINSEN VFKVCDEPHP LLVKEMIQHC VNANIDEAYK ILAHLWHLGY SPEDIIGNIF RVCKTFQMAE YLKLEFIKEI GYTHMKIAEG VNSLLQMAGL LARLCQKTMA PVAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards