About Pro-adrenomedullin
Pro-adrenomedullin (ADM) is a protein
from Homo sapiens identified by UniProt accession
P35318, 185 residues long.
MolForge cross-references it against 0 known binders and
639 disease associations.
Target properties
| Protein name | Pro-adrenomedullin |
|---|
| UniProt accession | P35318 |
|---|
| Gene | ADM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 185 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (639)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.23
- apolipoprotein A 1 measurement · score 0.22
- hemoglobin measurement · score 0.22
- lean body mass · score 0.22
- Varicose veins · score 0.22
- fat body mass · score 0.21
- neuroticism measurement · score 0.21
- erythrocyte count · score 0.21
- systolic blood pressure · score 0.21
- red blood cell density measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P35318-F1 | alphafold | PREDICTED | 61.85 | — |
Amino-acid sequence (185 residues)
MKLVSVALMY LGSLAFLGAD TARLDVASEF RKKWNKWALS RGKRELRMSS SYPTGLADVK AGPAQTLIRP QDMKGASRSP EDSSPDAARI RVKRYRQSMN NFQGLRSFGC RFGTCTVQKL AHQIYQFTDK DKDNVAPRSK ISPQGYGRRR RRSLPEAGPG RTLVSSKPQA HGAPAPPSGS APHFL
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