Serum amyloid A-4 protein (SAA4)

About Serum amyloid A-4 protein

Serum amyloid A-4 protein (SAA4) is a protein from Homo sapiens identified by UniProt accession P35542, 130 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Serum amyloid A-4 protein
UniProt accession	P35542
Gene	SAA4
Organism	Homo sapiens
Length	130 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.08
blood protein measurement · score 0.06
Rheumatoid arthritis · score 0.06
serum amyloid A-1 protein measurement · score 0.06
hepatocellular adenoma · score 0.04
neoplasm · score 0.04
non-small cell lung carcinoma · score 0.03
venous thromboembolism · score 0.03
urinary bladder carcinoma · score 0.03
cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P35542-F1	alphafold	PREDICTED	85.28	—

Amino-acid sequence (130 residues)

MRLFTGIVFC SLVMGVTSES WRSFFKEALQ GVGDMGRAYW DIMISNHQNS NRYLYARGNY DAAQRGPGGV WAAKLISRSR VYLQGLIDCY LFGNSSTVLE DSKSNEKAEE WGRSGKDPDR FRPDGLPKKY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards