About Basigin
Basigin (BSG) is a protein
from Homo sapiens identified by UniProt accession
P35613, 385 residues long.
MolForge cross-references it against 0 known binders and
676 disease associations.
Target properties
| Protein name | Basigin |
|---|
| UniProt accession | P35613 |
|---|
| Gene | BSG |
|---|
| Organism | Homo sapiens |
|---|
| Length | 385 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (676)
Diseases linked to this target (Open Targets).
- inborn errors of metabolism · score 0.37
- neurodegenerative disease · score 0.27
- breast adenocarcinoma · score 0.26
- neoplasm · score 0.12
- hepatocellular carcinoma · score 0.12
- cancer · score 0.12
- oral squamous cell carcinoma · score 0.11
- Rheumatoid arthritis · score 0.11
- non-small cell lung carcinoma · score 0.11
- melanoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P35613-F1 | alphafold | PREDICTED | 86.11 | — |
Amino-acid sequence (385 residues)
MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA GSAPLKSSGQ HQNDKGKNVR QRNSS
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