About Zinc finger protein 93
Zinc finger protein 93 (ZNF93) is a protein
from Homo sapiens identified by UniProt accession
P35789, 620 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Zinc finger protein 93 |
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| UniProt accession | P35789 |
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| Gene | ZNF93 |
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| Organism | Homo sapiens |
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| Length | 620 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (24)
Diseases linked to this target (Open Targets).
- nasopharyngeal neoplasm · score 0.14
- Down syndrome · score 0.07
- Shwachman-Diamond syndrome · score 0.03
- atypical hemolytic-uremic syndrome with C3 anomaly · score 0.03
- atypical hemolytic-uremic syndrome with thrombomodulin anomaly · score 0.03
- atypical hemolytic-uremic syndrome with I factor anomaly · score 0.03
- atypical hemolytic-uremic syndrome with MCP/CD46 anomaly · score 0.03
- Blackfan-Diamond anemia · score 0.03
- tubulointerstitial kidney disease, autosomal dominant, 2 · score 0.03
- atypical hemolytic-uremic syndrome with B factor anomaly · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P35789-F1 | alphafold | PREDICTED | 75.39 | — |
Amino-acid sequence (620 residues)
MGPLQFRDVA IEFSLEEWHC LDTAQRNLYR NVMLENYSNL VFLGIVVSKP DLIAHLEQGK KPLTMKRHEM VANPSVICSH FAQDLWPEQN IKDSFQKVIL RRYEKRGHGN LQLIKRCESV DECKVHTGGY NGLNQCSTTT QSKVFQCDKY GKVFHKFSNS NRHNIRHTEK KPFKCIECGK AFNQFSTLIT HKKIHTGEKP YICEECGKAF KYSSALNTHK RIHTGEKPYK CDKCDKAFIA SSTLSKHEII HTGKKPYKCE ECGKAFNQSS TLTKHKKIHT GEKPYKCEEC GKAFNQSSTL TKHKKIHTGE KPYVCEECGK AFKYSRILTT HKRIHTGEKP YKCNKCGKAF IASSTLSRHE FIHMGKKHYK CEECGKAFIW SSVLTRHKRV HTGEKPYKCE ECGKAFKYSS TLSSHKRSHT GEKPYKCEEC GKAFVASSTL SKHEIIHTGK KPYKCEECGK AFNQSSSLTK HKKIHTGEKP YKCEECGKAF NQSSSLTKHK KIHTGEKPYK CEECGKAFNQ SSTLIKHKKI HTREKPYKCE ECGKAFHLST HLTTHKILHT GEKPYRCREC GKAFNHSATL SSHKKIHSGE KPYECDKCGK AFISPSSLSR HEIIHTGEKP
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