About Zinc finger protein 76
Zinc finger protein 76 (ZNF76) is a protein
from Homo sapiens identified by UniProt accession
P36508, 570 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Zinc finger protein 76 |
|---|
| UniProt accession | P36508 |
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| Gene | ZNF76 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 570 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.35
- serum alanine aminotransferase measurement · score 0.31
- alkaline phosphatase measurement · score 0.30
- sex hormone-binding globulin measurement · score 0.29
- neutrophil count · score 0.28
- leukocyte count · score 0.28
- platelet crit · score 0.27
- C-reactive protein measurement · score 0.24
- asthma · score 0.24
- HbA1c measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P36508-F1 | alphafold | PREDICTED | 57.69 | — |
Amino-acid sequence (570 residues)
MESLGLHTVT LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ KEALSFEDGQ PVQLEDGSMA YIHRTPREGY DPSTLEAVQL EDGSTAYIHH PVAVPSESTI LAVQTEVGLE DLAAEDDEGF SADAVVALEQ YASKVLHDSQ IPRNGKGQQV GDRAFRCGYK GCGRLYTTAH HLKVHERAHT GDRPYRCDFP SCGKAFATGY GLKSHVRTHT GEKPYKCPEE LCSKAFKTSG DLQKHVRTHT GERPFQCPFE GCGRSFTTSN IRKVHVRTHT GERPYTCPEP HCGRGFTSAT NYKNHVRIHT GEKPYVCTVP GCGKRFTEYS SLYKHHVVHT HCKPYTCSTC GKTYRQTSTL AMHKRSAHGE LEATEESEQA LYEQQQLEAA SAAEESPPPK RPRIAYLSEV KEERDDIPAQ VAMVTEEDGA PQVALITQDG AQQVSLSPED LQALGSAISM VTQHGSTTLT IPSPDADLAT SGTHTVTMVS ADGTQTQPVT IITSGAVVAE DSSVASLRHQ QVALLATANG THIAVQLEEQ QTLEEAINVA TAAMQQGAVT LETTVSESGC
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