About Oxidized purine nucleoside triphosphate hydrolase
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) is a protein
from Homo sapiens identified by UniProt accession
P36639, 156 residues long.
MolForge cross-references it against 0 known binders and
201 disease associations.
Target properties
| Protein name | Oxidized purine nucleoside triphosphate hydrolase |
|---|
| UniProt accession | P36639 |
|---|
| Gene | NUDT1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 156 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (201)
Diseases linked to this target (Open Targets).
- plasminogen activator inhibitor 1 measurement · score 0.39
- mathematical ability · score 0.19
- self reported educational attainment · score 0.18
- adolescent idiopathic scoliosis · score 0.12
- cancer · score 0.11
- hepatocellular carcinoma · score 0.10
- glioblastoma multiforme · score 0.09
- non-small cell lung carcinoma · score 0.09
- nonpapillary renal cell carcinoma · score 0.09
- esophageal squamous cell carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P36639-F1 | alphafold | PREDICTED | 97.17 | — |
Amino-acid sequence (156 residues)
MGASRLYTLV LVLQPQRVLL GMKKRGFGAG RWNGFGGKVQ EGETIEDGAR RELQEESGLT VDALHKVGQI VFEFVGEPEL MDVHVFCTDS IQGTPVESDE MRPCWFQLDQ IPFKDMWPDD SYWFPLLLQK KKFHGYFKFQ GQDTILDYTL REVDTV
Explore Oxidized purine nucleoside triphosphate hydrolase with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets