Nuclear pore glycoprotein p62 (NUP62)

About Nuclear pore glycoprotein p62

Nuclear pore glycoprotein p62 (NUP62) is a protein from Homo sapiens identified by UniProt accession P37198, 522 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Nuclear pore glycoprotein p62
UniProt accession	P37198
Gene	NUP62
Organism	Homo sapiens
Length	522 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

infantile bilateral striatal necrosis · score 0.55
HIV infection · score 0.54
influenza · score 0.54
viral disease · score 0.53
familial infantile bilateral striatal necrosis · score 0.53
Histiocytosis · score 0.37
COVID-19 · score 0.37
clear cell renal carcinoma · score 0.28
age at menopause · score 0.25
breast adenocarcinoma · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P37198-F1	alphafold	PREDICTED	57.92	—

Amino-acid sequence (522 residues)

MSGFNFGGTG APTGGFTFGT AKTATTTPAT GFSFSTSGTG GFNFGAPFQP ATSTPSTGLF SLATQTPATQ TTGFTFGTAT LASGGTGFSL GIGASKLNLS NTAATPAMAN PSGFGLGSSN LTNAISSTVT SSQGTAPTGF VFGPSTTSVA PATTSGGFSF TGGSTAQPSG FNIGSAGNSA QPTAPATLPF TPATPAATTA GATQPAAPTP TATITSTGPS LFASIATAPT SSATTGLSLC TPVTTAGAPT AGTQGFSLKA PGAASGTSTT TSTAATATAT TTSSSSTTGF ALNLKPLAPA GIPSNTAAAV TAPPGPGAAA GAAASSAMTY AQLESLINKW SLELEDQERH FLQQATQVNA WDRTLIENGE KITSLHREVE KVKLDQKRLD QELDFILSQQ KELEDLLSPL EELVKEQSGT IYLQHADEER EKTYKLAENI DAQLKRMAQD LKDIIEHLNT SGAPADTSDP LQQICKILNA HMDSLQWIDQ NSALLQRKVE EVTKVCEGRR KEQERSFRIT FD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards