About Hippocalcin-like protein 1
Hippocalcin-like protein 1 (HPCAL1) is a protein
from Homo sapiens identified by UniProt accession
P37235, 193 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Hippocalcin-like protein 1 |
|---|
| UniProt accession | P37235 |
|---|
| Gene | HPCAL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.41
- urate measurement · score 0.39
- bone density · score 0.39
- body height · score 0.36
- age at menarche · score 0.34
- fat body mass · score 0.28
- base metabolic rate measurement · score 0.27
- whole body water mass · score 0.27
- appendicular lean mass · score 0.27
- platelet component distribution width · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P37235-F1 | alphafold | PREDICTED | 86.73 | — |
Amino-acid sequence (193 residues)
MGKQNSKLRP EVLQDLRENT EFTDHELQEW YKGFLKDCPT GHLTVDEFKK IYANFFPYGD ASKFAEHVFR TFDTNGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISRSE MLEIVQAIYK MVSSVMKMPE DESTPEKRTD KIFRQMDTNN DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA SQF
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