About Transgelin-2
Transgelin-2 (TAGLN2) is a protein
from Homo sapiens identified by UniProt accession
P37802, 199 residues long.
MolForge cross-references it against 0 known binders and
186 disease associations.
Target properties
| Protein name | Transgelin-2 |
|---|
| UniProt accession | P37802 |
|---|
| Gene | TAGLN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (186)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- mean platelet volume · score 0.38
- platelet component distribution width · score 0.35
- monocyte count · score 0.25
- breast adenocarcinoma · score 0.25
- glioblastoma multiforme · score 0.16
- brain measurement · score 0.11
- neoplasm · score 0.10
- cancer · score 0.10
- cortical surface area measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P37802-F1 | alphafold | PREDICTED | 88.12 | — |
Amino-acid sequence (199 residues)
MANRGPAYGL SREVQQKIEK QYDADLEQIL IQWITTQCRK DVGRPQPGRE NFQNWLKDGT VLCELINALY PEGQAPVKKI QASTMAFKQM EQISQFLQAA ERYGINTTDI FQTVDLWEGK NMACVQRTLM NLGGLAVARD DGLFSGDPNW FPKKSKENPR NFSDNQLQEG KNVIGLQMGT NRGASQAGMT GYGMPRQIL
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